Wolfram Syndrome is a rare genetic disorder which is also known as DIDMOAD syndrome after its 4 most common features (
Diabetes Insipidus, Diabetes Mellitus,
Optic Atrophy and
Deafness). Everyone with Wolfram Syndrome will have optic atrophy at some stage, which means that the optic nerve wastes away and causes
colour blindness and gradual loss of vision. Wolfram Syndrome is very rare and affects around 1 in 770,000 of the total UK population.